Divergent CFTR orthologs respond differently to the channel inhibitors CFTR(inh)-172, glibenclamide, and GlyH-101

Comparison of diverse orthologs is a powerful tool to study the structure and function of channel proteins. We investigated the response of human, killifish, pig, and shark cystic fibrosis transmembrane conductance regulator (CFTR) to specific inhibitors of the channel: CFTR(inh)-172, glibenclamide,...

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Bibliographic Details
Main Authors: Stahl, Maximilian, Stahl, Klaus, Brubacher, Marie B., Forrest, John N.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Membrane Transporters, Ion Channels and Pumps
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328903/
https://ncbi.nlm.nih.gov/pubmed/21940661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00225.2011
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