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Divergent CFTR orthologs respond differently to the channel inhibitors CFTR(inh)-172, glibenclamide, and GlyH-101
Comparison of diverse orthologs is a powerful tool to study the structure and function of channel proteins. We investigated the response of human, killifish, pig, and shark cystic fibrosis transmembrane conductance regulator (CFTR) to specific inhibitors of the channel: CFTR(inh)-172, glibenclamide,...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328903/ https://ncbi.nlm.nih.gov/pubmed/21940661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00225.2011 |
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