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Divergent CFTR orthologs respond differently to the channel inhibitors CFTR(inh)-172, glibenclamide, and GlyH-101

Comparison of diverse orthologs is a powerful tool to study the structure and function of channel proteins. We investigated the response of human, killifish, pig, and shark cystic fibrosis transmembrane conductance regulator (CFTR) to specific inhibitors of the channel: CFTR(inh)-172, glibenclamide,...

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Hlavní autoři: Stahl, Maximilian, Stahl, Klaus, Brubacher, Marie B., Forrest, John N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328903/
https://ncbi.nlm.nih.gov/pubmed/21940661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00225.2011
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