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An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a chloride channel central to the development of secretory diarrhea and cystic fibrosis. The oldest CFTR ortholog identified is from dogfish shark which retains similar structural and functional characteristics to the mammalian protei...
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| Publicat a: | Dev Cell |
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| Autors principals: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7665244/ https://ncbi.nlm.nih.gov/pubmed/31679858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.09.017 |
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