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Specific Stabilization of CFTR by Phosphatidylserine

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR, ABCC7) is a plasma membrane chloride ion channel in the ABC transporter superfamily. CFTR is a key target for cystic fibrosis drug development, and its structural elucidation would advance those efforts. However, the limited in vivo and...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Hildebrandt, Ellen, Khazanov, Netaly, Kappes, John C., Dai, Qun, Senderowitz, Hanoch, Urbatsch, Ina L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237360/
https://ncbi.nlm.nih.gov/pubmed/27913277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2016.11.013
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