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A Double Negative Feedback Loop between mTORC1 and AMPK Kinases Guarantees Precise Autophagy Induction upon Cellular Stress

Cellular homeostasis is controlled by an evolutionary conserved cellular digestive process called autophagy. This mechanism is tightly regulated by the two sensor elements called mTORC1 and AMPK. mTORC1 is one of the master regulators of proteostasis, while AMPK maintains cellular energy homeostasis...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Holczer, Marianna, Hajdú, Bence, Lőrincz, Tamás, Szarka, András, Bánhegyi, Gábor, Kapuy, Orsolya
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888297/
https://ncbi.nlm.nih.gov/pubmed/31703252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20225543
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