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GADD34 Keeps the mTOR Pathway Inactivated in Endoplasmic Reticulum Stress Related Autophagy

The balance of protein synthesis and proteolysis (i.e. proteostasis) is maintained by a complex regulatory network in which mTOR (mechanistic target of rapamycin serine/threonine kinase) pathway and unfolded protein response are prominent positive and negative actors. The interplay between the two s...

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Publicat a:PLoS One
Autors principals: Holczer, Marianna, Bánhegyi, Gábor, Kapuy, Orsolya
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161374/
https://ncbi.nlm.nih.gov/pubmed/27992581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168359
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