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Engineering of a synthetic quadrastable gene network to approach Waddington landscape and cell fate determination
The process of cell fate determination has been depicted intuitively as cells travelling and resting on a rugged landscape, which has been probed by various theoretical studies. However, few studies have experimentally demonstrated how underlying gene regulatory networks shape the landscape and henc...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5388541/ https://ncbi.nlm.nih.gov/pubmed/28397688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23702 |
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