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A deterministic map of Waddington's epigenetic landscape for cell fate specification

BACKGROUND: The image of the "epigenetic landscape", with a series of branching valleys and ridges depicting stable cellular states and the barriers between those states, has been a popular visual metaphor for cell lineage specification - especially in light of the recent discovery that te...

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Detalhes bibliográficos
Main Authors: Bhattacharya, Sudin, Zhang, Qiang, Andersen, Melvin E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213676/
https://ncbi.nlm.nih.gov/pubmed/21619617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-85
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