Tunable synthetic phenotypic diversification on Waddington’s landscape through autonomous signaling

Phenotypic diversification of cells is crucial for developmental and regenerative processes in multicellular organisms. The diversification concept is described as the motion of marbles rolling down Waddington’s landscape, in which the number of stable states changes as development proceeds. In cont...

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Bibliografiske detaljer
Main Authors: Sekine, Ryoji, Yamamura, Masayuki, Ayukawa, Shotaro, Ishimatsu, Kana, Akama, Satoru, Takinoue, Masahiro, Hagiya, Masami, Kiga, Daisuke
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207703/
https://ncbi.nlm.nih.gov/pubmed/22025684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105901108
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