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Engineering of regulated stochastic cell fate determination

Both microbes and multicellular organisms actively regulate their cell fate determination to cope with changing environments or to ensure proper development. Here, we use synthetic biology approaches to engineer bistable gene networks to demonstrate that stochastic and permanent cell fate determinat...

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Main Authors: Wu, Min, Su, Ri-Qi, Li, Xiaohui, Ellis, Tom, Lai, Ying-Cheng, Wang, Xiao
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696818/
https://ncbi.nlm.nih.gov/pubmed/23754391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305423110
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