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Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities

Multiple type I interferons (IFN-α/β) elicit Jak/Stat activation, rapid gene induction, and pleiotropic effects, such as differentiation, antiviral protection, and blocks in proliferation, which are dependent on the IFN subtype and the cellular context. To date, ligand- and receptor-specific molecul...

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書誌詳細
主要な著者: Moraga, Ignacio, Harari, Daniel, Schreiber, Gideon, Uzé, Gilles, Pellegrini, Sandra
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725717/
https://ncbi.nlm.nih.gov/pubmed/19564411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01808-08
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