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Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes

Type-I interferon (IFN)-induced activation of the mammalian target of rapamycin (mTOR) signaling pathway has been implicated in translational control of mRNAs encoding interferon-stimulated genes (ISGs). However, mTOR-sensitive translatomes commonly include mRNAs with a 5’ terminal oligopyrimidine t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Livingstone, Mark, Sikström, Kristina, Robert, Philippe A., Uzé, Gilles, Larsson, Ola, Pellegrini, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514843/
https://ncbi.nlm.nih.gov/pubmed/26207988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133482
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