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FUS contributes to mTOR-dependent inhibition of translation

The amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)–linked RNA-binding protein called FUS (fused in sarcoma) has been implicated in several aspects of RNA regulation, including mRNA translation. The mechanism by which FUS affects the translation of polyribosomes has not been es...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sévigny, Myriam, Bourdeau Julien, Isabelle, Venkatasubramani, Janani Priya, Hui, Jeremy B., Dutchak, Paul A., Sephton, Chantelle F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939483/
https://ncbi.nlm.nih.gov/pubmed/33082139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013801
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