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FUS contributes to mTOR-dependent inhibition of translation

The amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)–linked RNA-binding protein called FUS (fused in sarcoma) has been implicated in several aspects of RNA regulation, including mRNA translation. The mechanism by which FUS affects the translation of polyribosomes has not been es...

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Vydáno v:J Biol Chem
Hlavní autoři: Sévigny, Myriam, Bourdeau Julien, Isabelle, Venkatasubramani, Janani Priya, Hui, Jeremy B., Dutchak, Paul A., Sephton, Chantelle F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939483/
https://ncbi.nlm.nih.gov/pubmed/33082139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013801
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