The GTP/GDP Cycling of Rho GTPase TCL Is an Essential Regulator of the Early Endocytic Pathway

Rho GTPases are key regulators of actin dynamics. We report that the Rho GTPase TCL, which is closely related to Cdc42 and TC10, localizes to the plasma membrane and the early/sorting endosomes in HeLa cells, suggesting a role in the early endocytic pathway. Receptor-dependent internalization of tra...

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Publicado en:Mol Biol Cell
Autores principales: de Toledo, Marion, Senic-Matuglia, Francesca, Salamero, Jean, Uze, Gilles, Comunale, Franck, Fort, Philippe, Blangy, Anne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Cell Biology 2003
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Articles
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284789/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12960428/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-04-0254
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