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Interaction of Anesthetics with the Rho GTPase Regulator Rho GDP Dissociation Inhibitor

The physiological effects of anesthetics have been ascribed to their interaction with hydrophobic sites within functionally relevant CNS proteins. Studies have shown that volatile anesthetics compete for luciferin binding to the hydrophobic substrate binding site within firefly luciferase and inhibi...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Ho, Cojen, Shanmugasundararaj, Sivananthaperumal, Miller, Keith W., Malinowski, Steve A., Cook, Anthony C., Slater, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556268/
https://ncbi.nlm.nih.gov/pubmed/18702520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800544d
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