Interaction of Anesthetics with the Rho GTPase Regulator Rho GDP Dissociation Inhibitor

The physiological effects of anesthetics have been ascribed to their interaction with hydrophobic sites within functionally relevant CNS proteins. Studies have shown that volatile anesthetics compete for luciferin binding to the hydrophobic substrate binding site within firefly luciferase and inhibi...

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Udgivet i:Biochemistry
Main Authors: Ho, Cojen, Shanmugasundararaj, Sivananthaperumal, Miller, Keith W., Malinowski, Steve A., Cook, Anthony C., Slater, Simon J.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556268/
https://ncbi.nlm.nih.gov/pubmed/18702520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800544d
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