The Fer tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor α with the small GTPase Rac

BACKGROUND: RhoGDI proteins are important regulators of the small GTPase Rac, because they shuttle Rac from the cytoplasm to membranes and also protect Rac from activation, deactivation and degradation. How the binding and release of Rac from RhoGDI is regulated is not precisely understood. RESULTS:...

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Auteurs principaux: Fei, Fei, Kweon, Soo-Mi, Haataja, Leena, De Sepulveda, Paulo, Groffen, John, Heisterkamp, Nora
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009610/
https://ncbi.nlm.nih.gov/pubmed/21122136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-48
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