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The Fer tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor α with the small GTPase Rac

BACKGROUND: RhoGDI proteins are important regulators of the small GTPase Rac, because they shuttle Rac from the cytoplasm to membranes and also protect Rac from activation, deactivation and degradation. How the binding and release of Rac from RhoGDI is regulated is not precisely understood. RESULTS:...

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Hlavní autoři: Fei, Fei, Kweon, Soo-Mi, Haataja, Leena, De Sepulveda, Paulo, Groffen, John, Heisterkamp, Nora
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009610/
https://ncbi.nlm.nih.gov/pubmed/21122136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-48
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