The GTP/GDP Cycling of Rho GTPase TCL Is an Essential Regulator of the Early Endocytic Pathway

Rho GTPases are key regulators of actin dynamics. We report that the Rho GTPase TCL, which is closely related to Cdc42 and TC10, localizes to the plasma membrane and the early/sorting endosomes in HeLa cells, suggesting a role in the early endocytic pathway. Receptor-dependent internalization of tra...

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Autori principali: de Toledo, Marion, Senic-Matuglia, Francesca, Salamero, Jean, Uze, Gilles, Comunale, Franck, Fort, Philippe, Blangy, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2003
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC284789/
https://ncbi.nlm.nih.gov/pubmed/12960428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-04-0254
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