AKT and GSK-3 Are Necessary for Direct Ezrin Binding to NHE3 as Part of a C-terminal Stimulatory Complex: ROLE OF A NOVEL SER-RICH NHE3 C-TERMINAL MOTIF IN NHE3 ACTIVITY AND TRAFFI...

door Singh, Varsha, Lin, Rong, Yang, Jianbo, Cha, Boyoung, Sarker, Rafiquel, Tse, Chung Ming, Donowitz, Mark
Gepubliceerd in 2014

Phosphorylation of NHE3-S(719) regulates NHE3 activity through the formation of multiple signaling complexes

door Sarker, Rafiquel, Cha, Boyoung, Kovbasnjuk, Olga, Cole, Robert, Gabelli, Sandra, Tse, Chung Ming, Donowitz, Mark
Gepubliceerd in Mol Biol Cell (2017)

Cholinergic-induced anion secretion in murine jejunal enteroids involves synergy between muscarinic and nicotinic pathways

door Johnson, Kelli, Yin, Jianyi, In, Julie G., Kulkarni, Subhash, Pasricha, Pankaj, Tse, Chung Ming, Donowitz, Mark
Gepubliceerd in Am J Physiol Cell Physiol (2020)

Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3

door Govindarajan, Rajgopal, Leung, George P. H., Zhou, Mingyan, Tse, Chung-Ming, Wang, Joanne, Unadkat, Jashvant D
Gepubliceerd in 2009

cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity

door Tse, Chung-Ming, Yin, Jianyi, Singh, Varsha, Sarker, Rafiquel, Lin, Ruxian, Verkman, Alan S., Turner, Jerrold R., Donowitz, Mark
Gepubliceerd in Cell Mol Gastroenterol Hepatol (2019)

Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes

door Govindarajan, Rajgopal, Endres, Christopher J., Whittington, Dale, LeCluyse, Edward, Pastor-Anglada, Marçal, Tse, Chung-Ming, Unadkat, Jashvant D.
Gepubliceerd in 2008

The Spatial Organization of Proton and Lactate Transport in a Rat Brain Tumor

door Grillon, Emmanuelle, Farion, Régine, Fablet, Katell, De Waard, Michel, Tse, Chung Ming, Donowitz, Mark, Rémy, Chantal, Coles, Jonathan A.
Gepubliceerd in 2011

A common NHE3 single-nucleotide polymorphism has normal function and sensitivity to regulatory ligands

door Yin, Jianyi, Tse, Chung-Ming, Cha, Boyoung, Sarker, Rafiquel, Zhu, Xinjun C., Walentinsson, Anna, Greasley, Peter J., Donowitz, Mark
Gepubliceerd in Am J Physiol Gastrointest Liver Physiol (2017)

Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers

door Yin, Jianyi, Tse, Chung-Ming, Avula, Leela Rani, Singh, Varsha, Foulke-Abel, Jennifer, de Jonge, Hugo R., Donowitz, Mark
Gepubliceerd in Cell Mol Gastroenterol Hepatol (2018)

cAMP-mediated inhibition of the epithelial brush border Na(+)/H(+) exchanger, NHE3, requires an associated regulatory protein

door Yun, C. H. Chris, Oh, Soohyuk, Zizak, Mirza, Steplock, Deborah, Tsao, Su, Tse, Chung-Ming, Weinman, Edward J., Donowitz, Mark
Gepubliceerd in 1997

PDZ domain-dependent regulation of NHE3 protein by both internal Class II and C-terminal Class I PDZ-binding motifs

door Cha, Boyoung, Yang, Jianbo, Singh, Varsha, Zachos, Nicholas C., Sarker, Rafiquel I., Chen, Tian-e, Chakraborty, Molee, Tse, Chung-Ming, Donowitz, Mark
Gepubliceerd in J Biol Chem (2017)

Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip

door Yin, Jianyi, Sunuwar, Laxmi, Kasendra, Magdalena, Yu, Huimin, Tse, Chung-Ming, Talbot, C. Conover, Boronina, Tatiana, Cole, Robert, Karalis, Katia, Donowitz, Mark
Gepubliceerd in Am J Physiol Gastrointest Liver Physiol (2021)

Allergen challenge sensitizes TRPA1 in vagal sensory neurons and afferent C-fiber subtypes in guinea pig esophagus

door Liu, Zhenyu, Hu, Youtian, Yu, Xiaoyun, Xi, Jiefeng, Fan, Xiaoming, Tse, Chung-Ming, Myers, Allen C., Pasricha, Pankaj J., Li, Xingde, Yu, Shaoyong
Gepubliceerd in Am J Physiol Gastrointest Liver Physiol (2015)

Epac1 mediates protein kinase A–independent mechanism of forskolin-activated intestinal chloride secretion

door Hoque, Kazi Mirajul, Woodward, Owen M., van Rossum, Damian B., Zachos, Nicholas C., Chen, Linxi, Leung, George P.H., Guggino, William B., Guggino, Sandra E., Tse, Chung-Ming
Gepubliceerd in 2010

NHE3 Activity Is Dependent on Direct Phosphoinositide Binding at the N Terminus of Its Intracellular Cytosolic Region

door Mohan, Sachin, Tse, Chung Ming, Gabelli, Sandra B., Sarker, Rafiquel, Cha, Boyoung, Fahie, Kamau, Nadella, Mythili, Zachos, Nicholas C., Tu-Sekine, Becky, Raben, Daniel, Amzel, L. Mario, Donowitz, Mark
Gepubliceerd in 2010

Anoctamin 1/TMEM16A controls intestinal Cl(−) secretion induced by carbachol and cholera toxin

door Lee, Byeongjun, Hong, Gyu-Sang, Lee, Sung Hoon, Kim, Hyungsup, Kim, Ajung, Hwang, Eun Mi, Kim, Jiyoon, Lee, Min Goo, Yang, Jin-Young, Kweon, Mi-Na, Tse, Chung-Ming, Mark, Donowitz, Oh, Uhtaek
Gepubliceerd in Exp Mol Med (2019)

NHERF3 is necessary for Escherichia coli heat-stable enterotoxin-induced inhibition of NHE3: differences in signaling in mouse small intestine and Caco-2 cells

door Chen, Tiane, Lin, Ruxian, Avula, Leela, Sarker, Rafiquel, Yang, Jianbo, Cha, Boyoung, Tse, Chung Ming, McNamara, George, Seidler, Ursula, Waldman, Scott, Snook, Adam, Bijvelds, Marcel J.C., de Jonge, Hugo R, Li, Xuhang, Donowitz, Mark
Gepubliceerd in Am J Physiol Cell Physiol (2019)

SARS-COV-2 induced Diarrhea is inflammatory, Ca (2+) Dependent and involves activation of calcium activated Cl channels

door Donowitz, Mark, Tse, Chung-Ming, Dokladny, Karol, Rawat, Manmeet, Horwitz, Ivy, Ye, Chunyan, Kell, Alison, Lin, Ruxian, Lee, Sun, Guo, Chenxu, Tsai, Shang Jui, Cox, Andrea, Gould, Stephen, In, Julie, Bradfute, Steven, Zachos, Nicholas C., Kovbasnjuk, Olga
Gepubliceerd in bioRxiv (2021)

Rapamycin-inspired macrocycles with new target specificity

door Guo, Zufeng, Hong, Sam Y., Wang, Jingxin, Rehan, Shahid, Liu, Wukun, Peng, Hanjing, Das, Manisha, Li, Wei, Bhat, Shridhar, Peiffer, Brandon, Ullman, Brett R., Tse, Chung-Ming, Tarmakova, Zlatina, Schiene-Fischer, Cordelia, Fischer, Gunter, Coe, Imogen, Paavilainen, Ville O., Sun, Zhaoli, Liu, Jun O.
Gepubliceerd in Nat Chem (2018)