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AKT and GSK-3 Are Necessary for Direct Ezrin Binding to NHE3 as Part of a C-terminal Stimulatory Complex: ROLE OF A NOVEL SER-RICH NHE3 C-TERMINAL MOTIF IN NHE3 ACTIVITY AND TRAFFICKING
Basal activity of the BB Na(+)/H(+) exchanger NHE3 requires multiprotein complexes that form on its C terminus. One complex stimulates basal NHE3 activity and contains ezrin and phosphoinositides as major components; how it stimulates NHE3 activity is not known. This study tested the hypothesis that...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937621/ https://ncbi.nlm.nih.gov/pubmed/24398676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521336 |
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