The NHE3 Juxtamembrane Cytoplasmic Domain Directly Binds Ezrin: Dual Role in NHE3 Trafficking and Mobility in the Brush Border

Based on physiological studies, the epithelial brush-border (BB) Na(+)/H(+) antiporter3 (NHE3) seems to associate with the actin cytoskeleton both by binding to and independently of the PDZ domain containing proteins NHERF1 and NHERF2. We now show that NHE3 directly binds ezrin at a site in its C te...

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Hauptverfasser: Cha, Boyoung, Tse, Ming, Yun, Chris, Kovbasnjuk, Olga, Mohan, Sachin, Hubbard, Ann, Arpin, Monique, Donowitz, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2006
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474801/
https://ncbi.nlm.nih.gov/pubmed/16540524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-09-0843
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