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The NHE3 Juxtamembrane Cytoplasmic Domain Directly Binds Ezrin: Dual Role in NHE3 Trafficking and Mobility in the Brush Border

Based on physiological studies, the epithelial brush-border (BB) Na(+)/H(+) antiporter3 (NHE3) seems to associate with the actin cytoskeleton both by binding to and independently of the PDZ domain containing proteins NHERF1 and NHERF2. We now show that NHE3 directly binds ezrin at a site in its C te...

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Detalhes bibliográficos
Main Authors: Cha, Boyoung, Tse, Ming, Yun, Chris, Kovbasnjuk, Olga, Mohan, Sachin, Hubbard, Ann, Arpin, Monique, Donowitz, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474801/
https://ncbi.nlm.nih.gov/pubmed/16540524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-09-0843
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