AKT and GSK-3 Are Necessary for Direct Ezrin Binding to NHE3 as Part of a C-terminal Stimulatory Complex: ROLE OF A NOVEL SER-RICH NHE3 C-TERMINAL MOTIF IN NHE3 ACTIVITY AND TRAFFI...

por Singh, Varsha, Lin, Rong, Yang, Jianbo, Cha, Boyoung, Sarker, Rafiquel, Tse, Chung Ming, Donowitz, Mark
Publicado 2014

Phosphorylation of NHE3-S(719) regulates NHE3 activity through the formation of multiple signaling complexes

por Sarker, Rafiquel, Cha, Boyoung, Kovbasnjuk, Olga, Cole, Robert, Gabelli, Sandra, Tse, Chung Ming, Donowitz, Mark
Publicado en Mol Biol Cell (2017)

Cholinergic-induced anion secretion in murine jejunal enteroids involves synergy between muscarinic and nicotinic pathways

por Johnson, Kelli, Yin, Jianyi, In, Julie G., Kulkarni, Subhash, Pasricha, Pankaj, Tse, Chung Ming, Donowitz, Mark
Publicado en Am J Physiol Cell Physiol (2020)

Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3

por Govindarajan, Rajgopal, Leung, George P. H., Zhou, Mingyan, Tse, Chung-Ming, Wang, Joanne, Unadkat, Jashvant D
Publicado 2009

cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity

por Tse, Chung-Ming, Yin, Jianyi, Singh, Varsha, Sarker, Rafiquel, Lin, Ruxian, Verkman, Alan S., Turner, Jerrold R., Donowitz, Mark
Publicado en Cell Mol Gastroenterol Hepatol (2019)

Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes

por Govindarajan, Rajgopal, Endres, Christopher J., Whittington, Dale, LeCluyse, Edward, Pastor-Anglada, Marçal, Tse, Chung-Ming, Unadkat, Jashvant D.
Publicado 2008

The Spatial Organization of Proton and Lactate Transport in a Rat Brain Tumor

por Grillon, Emmanuelle, Farion, Régine, Fablet, Katell, De Waard, Michel, Tse, Chung Ming, Donowitz, Mark, Rémy, Chantal, Coles, Jonathan A.
Publicado 2011

A common NHE3 single-nucleotide polymorphism has normal function and sensitivity to regulatory ligands

por Yin, Jianyi, Tse, Chung-Ming, Cha, Boyoung, Sarker, Rafiquel, Zhu, Xinjun C., Walentinsson, Anna, Greasley, Peter J., Donowitz, Mark
Publicado en Am J Physiol Gastrointest Liver Physiol (2017)

Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers

por Yin, Jianyi, Tse, Chung-Ming, Avula, Leela Rani, Singh, Varsha, Foulke-Abel, Jennifer, de Jonge, Hugo R., Donowitz, Mark
Publicado en Cell Mol Gastroenterol Hepatol (2018)

cAMP-mediated inhibition of the epithelial brush border Na(+)/H(+) exchanger, NHE3, requires an associated regulatory protein

por Yun, C. H. Chris, Oh, Soohyuk, Zizak, Mirza, Steplock, Deborah, Tsao, Su, Tse, Chung-Ming, Weinman, Edward J., Donowitz, Mark
Publicado 1997

PDZ domain-dependent regulation of NHE3 protein by both internal Class II and C-terminal Class I PDZ-binding motifs

por Cha, Boyoung, Yang, Jianbo, Singh, Varsha, Zachos, Nicholas C., Sarker, Rafiquel I., Chen, Tian-e, Chakraborty, Molee, Tse, Chung-Ming, Donowitz, Mark
Publicado en J Biol Chem (2017)

Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip

por Yin, Jianyi, Sunuwar, Laxmi, Kasendra, Magdalena, Yu, Huimin, Tse, Chung-Ming, Talbot, C. Conover, Boronina, Tatiana, Cole, Robert, Karalis, Katia, Donowitz, Mark
Publicado en Am J Physiol Gastrointest Liver Physiol (2021)

Allergen challenge sensitizes TRPA1 in vagal sensory neurons and afferent C-fiber subtypes in guinea pig esophagus

por Liu, Zhenyu, Hu, Youtian, Yu, Xiaoyun, Xi, Jiefeng, Fan, Xiaoming, Tse, Chung-Ming, Myers, Allen C., Pasricha, Pankaj J., Li, Xingde, Yu, Shaoyong
Publicado en Am J Physiol Gastrointest Liver Physiol (2015)

Epac1 mediates protein kinase A–independent mechanism of forskolin-activated intestinal chloride secretion

por Hoque, Kazi Mirajul, Woodward, Owen M., van Rossum, Damian B., Zachos, Nicholas C., Chen, Linxi, Leung, George P.H., Guggino, William B., Guggino, Sandra E., Tse, Chung-Ming
Publicado 2010

NHE3 Activity Is Dependent on Direct Phosphoinositide Binding at the N Terminus of Its Intracellular Cytosolic Region

por Mohan, Sachin, Tse, Chung Ming, Gabelli, Sandra B., Sarker, Rafiquel, Cha, Boyoung, Fahie, Kamau, Nadella, Mythili, Zachos, Nicholas C., Tu-Sekine, Becky, Raben, Daniel, Amzel, L. Mario, Donowitz, Mark
Publicado 2010

Anoctamin 1/TMEM16A controls intestinal Cl(−) secretion induced by carbachol and cholera toxin

por Lee, Byeongjun, Hong, Gyu-Sang, Lee, Sung Hoon, Kim, Hyungsup, Kim, Ajung, Hwang, Eun Mi, Kim, Jiyoon, Lee, Min Goo, Yang, Jin-Young, Kweon, Mi-Na, Tse, Chung-Ming, Mark, Donowitz, Oh, Uhtaek
Publicado en Exp Mol Med (2019)

NHERF3 is necessary for Escherichia coli heat-stable enterotoxin-induced inhibition of NHE3: differences in signaling in mouse small intestine and Caco-2 cells

por Chen, Tiane, Lin, Ruxian, Avula, Leela, Sarker, Rafiquel, Yang, Jianbo, Cha, Boyoung, Tse, Chung Ming, McNamara, George, Seidler, Ursula, Waldman, Scott, Snook, Adam, Bijvelds, Marcel J.C., de Jonge, Hugo R, Li, Xuhang, Donowitz, Mark
Publicado en Am J Physiol Cell Physiol (2019)

SARS-COV-2 induced Diarrhea is inflammatory, Ca (2+) Dependent and involves activation of calcium activated Cl channels

por Donowitz, Mark, Tse, Chung-Ming, Dokladny, Karol, Rawat, Manmeet, Horwitz, Ivy, Ye, Chunyan, Kell, Alison, Lin, Ruxian, Lee, Sun, Guo, Chenxu, Tsai, Shang Jui, Cox, Andrea, Gould, Stephen, In, Julie, Bradfute, Steven, Zachos, Nicholas C., Kovbasnjuk, Olga
Publicado en bioRxiv (2021)

Rapamycin-inspired macrocycles with new target specificity

por Guo, Zufeng, Hong, Sam Y., Wang, Jingxin, Rehan, Shahid, Liu, Wukun, Peng, Hanjing, Das, Manisha, Li, Wei, Bhat, Shridhar, Peiffer, Brandon, Ullman, Brett R., Tse, Chung-Ming, Tarmakova, Zlatina, Schiene-Fischer, Cordelia, Fischer, Gunter, Coe, Imogen, Paavilainen, Ville O., Sun, Zhaoli, Liu, Jun O.
Publicado en Nat Chem (2018)