Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation

Por Chen, Wen Yong, Townes, Tim M.
Publicado em 2000

Broad T-Cell Receptor Repertoire in T-Lymphocytes Derived from Human Induced Pluripotent Stem Cells

Por Chang, Chia-Wei, Lai, Yi-Shin, Lamb, Lawrence S., Townes, Tim M.
Publicado em 2014

Negative Regulation of IRF7 Activation by ATF4 Suggests a Cross Regulation Between the Interferon Responses and the Cellular Integrated Stress Responses

Por Liang, Qiming, Deng, Hongying, Sun, Chiao-Wang, Townes, Tim M., Zhu, Fanxiu
Publicado em 2010

Role of the b93cys, ATP and adenosine in red cell dependent hypoxic vasorelaxation

Por Liu, Yanping, Sun, Chiao-Wang, Honavar, Jaideep, Townes, Tim, Patel, Rakesh P
Publicado em 2013

Rapid tagging of endogenous mouse genes by recombineering and ES cell complementation of tetraploid blastocysts

Por Zhou, Dewang, Ren, Jin-Xiang, Ryan, Thomas M., Higgins, N. Patrick, Townes, Tim M.
Publicado em 2004

Mouse model of congenital polycythemia: Homologous replacement of murine gene by mutant human erythropoietin receptor gene

Por Divoky, Vladimir, Liu, Zhiyong, Ryan, Thomas M., Prchal, Jaroslav F., Townes, Tim M., Prchal, Josef T.
Publicado em 2001

Trichostatin A Up-Regulates Human Papillomavirus Type 11 Upstream Regulatory Region-E6 Promoter Activity in Undifferentiated Primary Human Keratinocytes

Por Zhao, Wei, Noya, Francisco, Chen, Wen Yong, Townes, Tim M., Chow, Louise T., Broker, Thomas R.
Publicado em 1999

Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase

Por Chen, Wen Yong, Bailey, Evans C., McCune, Steven L., Dong, Jian-Yun, Townes, Tim M.
Publicado em 1997

Correction of sickle cell disease by homologous recombination in embryonic stem cells

Por Wu, Li-Chen, Sun, Chiao-Wang, Ryan, Thomas M., Pawlik, Kevin M., Ren, Jinxiang, Townes, Tim M.
Publicado em 2006

SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency

Por Lai, Yi-Shin, Chang, Chia-Wei, Pawlik, Kevin M., Zhou, Dewang, Renfrow, Matthew B., Townes, Tim M.
Publicado em 2012

The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells

Por Yang, Zhenhua, Augustin, Jonathan, Chang, Chenbei, Hu, Jing, Shah, Kushani, Chang, Chia-Wei, Townes, Tim, Jiang, Hao
Publicado no Blood (2014)

Alterations in Expression and Chromatin Configuration of the Alpha Hemoglobin-Stabilizing Protein Gene in Erythroid Krüppel-Like Factor-Deficient Mice

Por Pilon, Andre M., Nilson, Douglas G., Zhou, Dewang, Sangerman, Jose, Townes, Tim M., Bodine, David M., Gallagher, Patrick G.
Publicado em 2006

Sickle Cells Abolish Melanoma Tumorigenesis in Hemoglobin SS Knockin Mice and Augment the Tumoricidal Effect of Oncolytic Virus In Vivo

Por Sun, Chiang Wang, Willmon, Candice, Wu, Li-Chen, Knopick, Peter, Thoerner, Jutta, Vile, Richard, Townes, Tim M., Terman, David S.
Publicado no Front Oncol (2016)

Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis

Por Suragani, Rajasekhar N. V. S., Zachariah, Roshini S., Velazquez, Jason G., Liu, Sijin, Sun, Chiao-Wang, Townes, Tim M., Chen, Jane-Jane
Publicado em 2012

ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo

Por Lange, Philipp S., Chavez, Juan C., Pinto, John T., Coppola, Giovanni, Sun, Chiao-Wang, Townes, Tim M., Geschwind, Daniel H., Ratan, Rajiv R.
Publicado em 2008

Atf4 Regulates Obesity, Glucose Homeostasis, and Energy Expenditure

Por Seo, Jin, Fortuno, Edgardo S., Suh, Jae Myoung, Stenesen, Drew, Tang, Wei, Parks, Elizabeth J., Adams, Christopher M., Townes, Tim, Graff, Jonathan M.
Publicado em 2009

Endothelin‐1 contributes to the progression of renal injury in sickle cell disease via reactive oxygen species

Por Brett Heimlich, J, Speed, Joshua S, O'Connor, Paul M, Pollock, Jennifer S, Townes, Tim M, Meiler, Steffen E, Kutlar, Abdullah, Pollock, David M
Publicado no Br J Pharmacol (2016)

Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation

Por Hiratani, Ichiro, Ryba, Tyrone, Itoh, Mari, Yokochi, Tomoki, Schwaiger, Michaela, Chang, Chia-Wei, Lyou, Yung, Townes, Tim M, Schübeler, Dirk, Gilbert, David M
Publicado em 2008

Peroxiredoxin-2 Recycling Is Inhibited During Erythrocyte Storage

Por Harper, Victoria M., Oh, Joo Yeun, Stapley, Ryan, Marques, Marisa B., Wilson, Landon, Barnes, Stephen, Sun, Chiao-Wang, Townes, Tim, Patel, Rakesh P.
Publicado no Antioxid Redox Signal (2015)

The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis

Por Shao, Zhicheng, Zhang, Ruowen, Khodadadi-Jamayran, Alireza, Chen, Bo, Crowley, Michael R., Festok, Muhamad A., Crossman, David K., Townes, Tim M., Hu, Kejin
Publicado no Nat Commun (2016)