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ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo

Oxidative stress is pathogenic in neurological diseases, including stroke. The identity of oxidative stress–inducible transcription factors and their role in propagating the death cascade are not well known. In an in vitro model of oxidative stress, the expression of the bZip transcription factor ac...

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Detalhes bibliográficos
Main Authors: Lange, Philipp S., Chavez, Juan C., Pinto, John T., Coppola, Giovanni, Sun, Chiao-Wang, Townes, Tim M., Geschwind, Daniel H., Ratan, Rajiv R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373852/
https://ncbi.nlm.nih.gov/pubmed/18458112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071460
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