Arginase 1 Regulation of Nitric Oxide Production Is Key to Survival of Trophic Factor-Deprived Motor Neurons

When deprived of trophic factors, the majority of cultured motor neurons undergo nitric oxide-dependent apoptosis. However, for reasons that have remained unclear, 30–50% of the motor neurons survive for several days without trophic factors. Here we hypothesize that the resistance of this motor neur...

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Détails bibliographiques
Auteurs principaux: Estévez, Alvaro G., Sahawneh, Mary Anne, Lange, Philipp S., Bae, Narae, Egea, Mariela, Ratan, Rajiv R.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2006
Sujets:
Brief Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570095/
https://ncbi.nlm.nih.gov/pubmed/16914676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0728-06.2006
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