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Rapid tagging of endogenous mouse genes by recombineering and ES cell complementation of tetraploid blastocysts
The construction of knockin vectors designed to modify endogenous genes in embryonic stem (ES) cells and the generation of mice from these modified cells is time consuming. The timeline of an experiment from the conception of an idea to the availability of mature mice is at least 9 months. We descri...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC519128/ https://ncbi.nlm.nih.gov/pubmed/15356288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh128 |
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