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Completely ES Cell-Derived Mice Produced by Tetraploid Complementation Using Inner Cell Mass (ICM) Deficient Blastocysts

Tetraploid complementation is often used to produce mice from embryonic stem cells (ESCs) by injection of diploid (2n) ESCs into tetraploid (4n) blastocysts (ESC-derived mice). This method has also been adapted to mouse cloning and the derivation of mice from induced pluripotent stem (iPS) cells. Ho...

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Main Authors: Wen, Duancheng, Saiz, Nestor, Rosenwaks, Zev, Hadjantonakis, Anna-Katerina, Rafii, Shahin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986396/
https://ncbi.nlm.nih.gov/pubmed/24733255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094730
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