GATA6 Levels Modulate Primitive Endoderm Cell Fate Choice and Timing in the Mouse Blastocyst

Cells of the inner cell mass (ICM) of the mouse blastocyst differentiate into the pluripotent epiblast (EPI) or the primitive endoderm (PrE), marked by the transcription factors NANOG and GATA6, respectively. To investigate the mechanistic regulation of this process, we applied an unbiased, quantita...

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Bibliographic Details
Main Authors: Schrode, Nadine, Saiz, Nestor, Di Talia, Stefano, Hadjantonakis, Anna-Katerina
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103658/
https://ncbi.nlm.nih.gov/pubmed/24835466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.011
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