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GATA6 Levels Modulate Primitive Endoderm Cell Fate Choice and Timing in the Mouse Blastocyst

Cells of the inner cell mass (ICM) of the mouse blastocyst differentiate into the pluripotent epiblast (EPI) or the primitive endoderm (PrE), marked by the transcription factors NANOG and GATA6, respectively. To investigate the mechanistic regulation of this process, we applied an unbiased, quantita...

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Autores principales: Schrode, Nadine, Saiz, Nestor, Di Talia, Stefano, Hadjantonakis, Anna-Katerina
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103658/
https://ncbi.nlm.nih.gov/pubmed/24835466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.011
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