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GATA6 Levels Modulate Primitive Endoderm Cell Fate Choice and Timing in the Mouse Blastocyst

Cells of the inner cell mass (ICM) of the mouse blastocyst differentiate into the pluripotent epiblast (EPI) or the primitive endoderm (PrE), marked by the transcription factors NANOG and GATA6, respectively. To investigate the mechanistic regulation of this process, we applied an unbiased, quantita...

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Main Authors: Schrode, Nadine, Saiz, Nestor, Di Talia, Stefano, Hadjantonakis, Anna-Katerina
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103658/
https://ncbi.nlm.nih.gov/pubmed/24835466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.011
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