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Endothelin‐1 contributes to the progression of renal injury in sickle cell disease via reactive oxygen species

BACKGROUND AND PURPOSE: Endothelin‐1 (ET‐1) is increased in patients with sickle cell disease and may contribute to the development of sickle cell nephropathy. The current study was designed to determine whether ET‐1 acting via the ET(A) receptor contributes to renal injury in a mouse model of sickl...

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Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Brett Heimlich, J, Speed, Joshua S, O'Connor, Paul M, Pollock, Jennifer S, Townes, Tim M, Meiler, Steffen E, Kutlar, Abdullah, Pollock, David M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940621/
https://ncbi.nlm.nih.gov/pubmed/26561980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13380
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