Long-Term Endothelin-A Receptor Antagonism Provides Robust Renal Protection in Humanized Sickle Cell Disease Mice

Sickle cell disease (SCD)–associated nephropathy is a major source of morbidity and mortality in patients because of the lack of efficacious treatments targeting renal manifestations of the disease. Here, we describe a long-term treatment strategy with the selective endothelin-A receptor (ET(A)) ant...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Kasztan, Malgorzata, Fox, Brandon M., Speed, Joshua S., De Miguel, Carmen, Gohar, Eman Y., Townes, Tim M., Kutlar, Abdullah, Pollock, Jennifer S., Pollock, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533228/
https://ncbi.nlm.nih.gov/pubmed/28348063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016070711
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados