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Endothelin‐1 contributes to the progression of renal injury in sickle cell disease via reactive oxygen species
BACKGROUND AND PURPOSE: Endothelin‐1 (ET‐1) is increased in patients with sickle cell disease and may contribute to the development of sickle cell nephropathy. The current study was designed to determine whether ET‐1 acting via the ET(A) receptor contributes to renal injury in a mouse model of sickl...
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| Veröffentlicht in: | Br J Pharmacol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940621/ https://ncbi.nlm.nih.gov/pubmed/26561980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13380 |
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