Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL

por Sulis, Maria Luisa, Saftig, Paul, Ferrando, Adolfo
Publicado em 2011

A conserved tetraspanin subfamily promotes Notch signaling in Caenorhabditis elegans and in human cells

por Dunn, Cory D., Sulis, Maria Luisa, Ferrando, Adolfo A., Greenwald, Iva
Publicado em 2010

Diagnostic yield of bronchoalveolar lavage in immunocompromised children with malignant and non‐malignant disorders

por Nadimpalli, Sruti, Foca, Marc, Satwani, Prakash, Sulis, Maria Luisa, Constantinescu, Andrei, Saiman, Lisa
Publicado no Pediatr Pulmonol (2017)

The SCF(FBW7) ubiquitin ligase complex as a tumor suppressor in T cell leukemia

por Thompson, Benjamin J., Buonamici, Silvia, Sulis, Maria Luisa, Palomero, Teresa, Vilimas, Tomas, Basso, Giuseppe, Ferrando, Adolfo, Aifantis, Iannis
Publicado em 2007

NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL

por Sulis, Maria Luisa, Williams, Odette, Palomero, Teresa, Tosello, Valeria, Pallikuppam, Sasikala, Real, Pedro J., Barnes, Kelly, Zuurbier, Linda, Meijerink, Jules P., Ferrando, Adolfo A.
Publicado em 2008

Activation of the PI3K Pathway in Cancer through Inhibition of PTEN by Exchange Factor P-REX2a

por Fine, Barry, Hodakoski, Cindy, Koujak, Susan, Su, Tao, Saal, Lao H., Maurer, Matthew, Hopkins, Benjamin, Keniry, Megan, Sulis, Maria Luisa, Mense, Sarah, Hibshoosh, Hanina, Parsons, Ramon
Publicado em 2009

Disregulated expression of the transcription factor ThPOK during T-cell development leads to high incidence of T-cell lymphomas

por Lee, Hyung-Ok, He, Xiao, Mookerjee-Basu, Jayati, Zhongping, Dai, Hua, Xiang, Nicolas, Emmanuelle, Sulis, Maria Luisa, Ferrando, Adolfo A., Testa, Joseph R., Kappes, Dietmar J.
Publicado no Proc Natl Acad Sci U S A (2015)

Identification of a secondary RET mutation in a pediatric patient with relapsed acute myeloid leukemia leads to the diagnosis and treatment of asymptomatic metastatic medullary thy...

por Pendrick, Danielle M., Oberg, Jennifer A., Hsiao, Susan J., Chung, Wendy K., Koval, Carrie, Sireci, Anthony, Kuo, Jennifer H., Satwani, Prakash, Glasser, Chana L., Sulis, Maria Luisa, Mansukhani, Mahesh M., Glade Bender, Julia L.
Publicado no Cold Spring Harb Mol Case Stud (2019)

Gamma-secretase inhibitors reverse glucocorticoid resistance in T-ALL

por Real, Pedro J., Tosello, Valeria, Palomero, Teresa, Castillo, Mireia, Hernando, Eva, de Stanchina, Elisa, Sulis, Maria Luisa, Barnes, Kelly, Sawai, Catherine, Homminga, Irene, Meijerink, Jules, Aifantis, Iannis, Basso, Giuseppe, Cordon-Cardo, Carlos, Ai, Walden, Ferrando, Adolfo
Publicado em 2008

Precision Medicine in Children and Young Adults with Hematologic Malignancies and Blood Disorders: The Columbia University Experience

por Marks, Lianna J., Oberg, Jennifer A., Pendrick, Danielle, Sireci, Anthony N., Glasser, Chana, Coval, Carrie, Zylber, Rebecca J., Chung, Wendy K., Pang, Jiuhong, Turk, Andrew T., Hsiao, Susan J., Mansukhani, Mahesh M., Glade Bender, Julia L., Kung, Andrew L., Sulis, Maria Luisa
Publicado no Front Pediatr (2017)

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

por Palomero, Teresa, Lim, Wei Keat, Odom, Duncan T., Sulis, Maria Luisa, Real, Pedro J., Margolin, Adam, Barnes, Kelly C., O'Neil, Jennifer, Neuberg, Donna, Weng, Andrew P., Aster, Jon C., Sigaux, Francois, Soulier, Jean, Look, A. Thomas, Young, Richard A., Califano, Andrea, Ferrando, Adolfo A.
Publicado em 2006

A secreted PTEN phosphatase that enters cells to alter signaling and survival

por Hopkins, Benjamin D., Fine, Barry, Steinbach, Nicole, Dendy, Meaghan, Rapp, Zachary, Shaw, Jacquelyn, Pappas, Kyrie, Yu, Jennifer S., Hodakoski, Cindy, Mense, Sarah, Klein, Joshua, Pegno, Sarah, Sulis, Maria-Luisa, Goldstein, Hannah, Amendolara, Benjamin, Lei, Liang, Maurer, Matthew, Bruce, Jeffrey, Canoll, Peter, Hibshoosh, Hanina, Parsons, Ramon
Publicado em 2013

Multi-site external validation of a risk prediction model for the diagnosis of blood stream infection in febrile pediatric oncology patients without severe neutropenia

por Esbenshade, Adam J., Zhao, Zhiguo, Aftandilian, Catherine, Saab, Raya, Wattier, Rachel L., Beauchemin, Melissa, Miller, Tamara P., Wilkes, Jennifer J., Kelly, Michael J., Fernbach, Alison, Jeng, Michael, Schwartz, Cindy L., Dvorak, Christopher C., Shyr, Yu, Moons, Karl G M, Sulis, Maria-Luisa, Friedman, Debra L.
Publicado no Cancer (2017)

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

por Palomero, Teresa, Sulis, Maria Luisa, Cortina, Maria, Real, Pedro J., Barnes, Kelly, Ciofani, Maria, Caparros, Esther, Buteau, Jean, Brown, Kristy, Perkins, Sherrie L., Bhagat, Govind, Mishra, Archana, Basso, Giuseppe, Castillo, Mireia, Nagase, Satoru, Cordon-Cardo, Carlos, Parsons, Ramon, Zúñiga-Pflücker, Juan Carlos, Dominguez, Maria, Ferrando, Adolfo A.
Publicado em 2007

Covalent inhibition of NSD1 histone methyltransferase

por Huang, Huang, Howard, Christina A., Zari, Sergei, Cho, Hyo Je, Shukla, Shirish, Li, Hao, Ndoj, Juliano, González-Alonso, Paula, Nikolaidis, Caroline, Abbott, Joshua, Rogawski, David S., Potopnyk, Mykhaylo A., Kempinska, Katarzyna, Miao, Hongzhi, Purohit, Trupta, Henderson, Andrew, Mapp, Anna, Sulis, Maria Luisa, Ferrando, Adolfo, Grembecka, Jolanta, Cierpicki, Tomasz
Publicado no Nat Chem Biol (2020)

Clonal evolution mechanisms in NT5C2 mutant relapsed acute lymphoblastic leukemia

por Tzoneva, Gannie, Dieck, Chelsea L., Oshima, Koichi, Ambesi-Impiombato, Alberto, Sánchez-Martín, Marta, Madubata, Chioma J., Khiabanian, Hossein, Yu, Jiangyan, Waanders, Esme, Iacobucci, Ilaria, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Loh, Mignon L., Kirschner-Schwabe, Renate, Mullighan, Charles G., Rabadan, Raul, Ferrando, Adolfo A.
Publicado no Nature (2018)

WT1 mutations in T-ALL

por Tosello, Valeria, Mansour, Marc R., Barnes, Kelly, Paganin, Maddalena, Sulis, Maria Luisa, Jenkinson, Sarah, Allen, Christopher G., Gale, Rosemary E., Linch, David C., Palomero, Teresa, Real, Pedro, Murty, Vundavalli, Yao, Xiaopan, Richards, Susan M., Goldstone, Anthony, Rowe, Jacob, Basso, Giuseppe, Wiernik, Peter H., Paietta, Elisabeth, Pieters, Rob, Horstmann, Martin, Meijerink, Jules P. P., Ferrando, Adolfo A.
Publicado em 2009

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

por Oshima, Koichi, Khiabanian, Hossein, da Silva-Almeida, Ana C., Tzoneva, Gannie, Abate, Francesco, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Carpenter, Zachary, Penson, Alex, Perez-Garcia, Arianne, Eckert, Cornelia, Nicolas, Concepción, Balbin, Milagros, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Devidas, Meenakshi, Loh, Mignon L., Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo A.
Publicado no Proc Natl Acad Sci U S A (2016)

Implementation of next generation sequencing into pediatric hematology-oncology practice: moving beyond actionable alterations

por Oberg, Jennifer A., Glade Bender, Julia L., Sulis, Maria Luisa, Pendrick, Danielle, Sireci, Anthony N., Hsiao, Susan J., Turk, Andrew T., Dela Cruz, Filemon S., Hibshoosh, Hanina, Remotti, Helen, Zylber, Rebecca J., Pang, Jiuhong, Diolaiti, Daniel, Koval, Carrie, Andrews, Stuart J., Garvin, James H., Yamashiro, Darrell J., Chung, Wendy K., Emerson, Stephen G., Nagy, Peter L., Mansukhani, Mahesh M., Kung, Andrew L.
Publicado no Genome Med (2016)

Refining risk classification in childhood B acute lymphoblastic leukemia: results of DFCI ALL Consortium Protocol 05-001

por Vrooman, Lynda M., Blonquist, Traci M., Harris, Marian H., Stevenson, Kristen E., Place, Andrew E., Hunt, Sarah K., O’Brien, Jane E., Asselin, Barbara L., Athale, Uma H., Clavell, Luis A., Cole, Peter D., Kelly, Kara M., Laverdiere, Caroline, Leclerc, Jean-Marie, Michon, Bruno, Schorin, Marshall A., Sulis, Maria Luisa, Welch, Jennifer J. G., Neuberg, Donna S., Sallan, Stephen E., Silverman, Lewis B.
Publicado no Blood Adv (2018)