Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3

Por Milligan, Graeme, Stoddart, Leigh A, Smith, Nicola J
Publicado em 2009

Effect of a toggle switch mutation in TM6 of the human adenosine A(3) receptor on Gi protein-dependent signalling and Gi-independent receptor internalization

Por Stoddart, Leigh A, Kellam, Barrie, Briddon, Stephen J, Hill, Stephen J
Publicado em 2014

Use of a new proximity assay (NanoBRET) to investigate the ligand‐binding characteristics of three fluorescent ligands to the human β (1)‐adrenoceptor expressed in HEK‐293 cells...

Por Soave, Mark, Stoddart, Leigh A., Brown, Alastair, Woolard, Jeanette, Hill, Stephen J.
Publicado no Pharmacol Res Perspect (2016)

The Action and Mode of Binding of Thiazolidinedione Ligands at Free Fatty Acid Receptor 1

Por Smith, Nicola J., Stoddart, Leigh A., Devine, Nicola M., Jenkins, Laura, Milligan, Graeme
Publicado em 2009

Allosteric interactions across native adenosine-A(3) receptor homodimers: quantification using single-cell ligand-binding kinetics

Por May, Lauren T., Bridge, Lloyd J., Stoddart, Leigh A., Briddon, Stephen J., Hill, Stephen J.
Publicado em 2011

Functional Homomers and Heteromers of Dopamine D(2L) and D(3) Receptors Co-exist at the Cell Surface

Por Pou, Chantevy, Mannoury la Cour, Clotilde, Stoddart, Leigh A., Millan, Mark J., Milligan, Graeme
Publicado em 2012

Fluorescence‐ and bioluminescence‐based approaches to study GPCR ligand binding

Por Stoddart, Leigh A, White, Carl W, Nguyen, Kim, Hill, Stephen J, Pfleger, Kevin D G
Publicado no Br J Pharmacol (2015)

Fragment Screening at Adenosine-A(3) Receptors in Living Cells Using a Fluorescence-Based Binding Assay

Por Stoddart, Leigh A., Vernall, Andrea J., Denman, Jessica L., Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Publicado em 2012

Application of BRET to monitor ligand binding to GPCRs

Por Stoddart, Leigh A, Johnstone, Elizabeth K M, Wheal, Amanda J, Goulding, Joëlle, Robers, Matthew B, Machleidt, Thomas, Wood, Keith V, Hill, Stephen J, Pfleger, Kevin D G
Publicado no Nat Methods (2015)

Extracellular Loop 2 of the Free Fatty Acid Receptor 2 Mediates Allosterism of a Phenylacetamide Ago-Allosteric Modulator

Por Smith, Nicola J., Ward, Richard J., Stoddart, Leigh A., Hudson, Brian D., Kostenis, Evi, Ulven, Trond, Morris, Joanne C., Tränkle, Christian, Tikhonova, Irina G., Adams, David R., Milligan, Graeme
Publicado em 2011