New insights into T cell biology and T cell-directed therapy for autoimmunity, inflammation, and immunosuppression

Por Steward-Tharp, Scott M., Song, Yun-jeong, Siegel, Richard M., O'Shea, John J.
Publicado em 2010

Signal transduction and Th17 cell differentiation

Por O’Shea, John J., Steward-Tharp, Scott M., Laurence, Arian, Watford, Wendy T., Wei, Lai, Adamson, Adewole S., Fan, Samuel
Publicado em 2009

IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation

Por Renavikar, Pranav S., Sinha, Sushmita, Brate, Ashley A., Borcherding, Nicholas, Crawford, Michael P., Steward-Tharp, Scott M., Karandikar, Nitin J.
Publicado no Front Immunol (2020)

Tofacitinib Suppresses Antibody Responses to Protein Therapeutics in Murine Hosts()

Por Onda, Masanori, Ghoreschi, Kamran, Steward-Tharp, Scott, Thomas, Craig, O’Shea, John J., Pastan, Ira H., FitzGerald, David J.
Publicado em 2014

Altered expression of SIRPγ on the T-cells of relapsing remitting multiple sclerosis and type 1 diabetes patients could potentiate effector responses from T-cells

Por Sinha, Sushmita, Renavikar, Pranav S., Crawford, Michael P., Steward-Tharp, Scott M., Brate, Ashley, Tsalikian, Eva, Tansey, Michael, Shivapour, Ezzatollah T., Cho, Tracey, Kamholz, John, Karandikar, Nitin J.
Publicado no PLoS One (2020)

Opposing regulation of the Il17 locus through direct, reciprocal actions of STAT3 and STAT5

Por Yang, Xiang-Ping, Ghoreschi, Kamran, Steward-Tharp, Scott M., Rodriguez-Canales, Jaime, Zhu, Jinfang, Grainger, John R., Hirahara, Kiyoshi, Sun, Hong-Wei, Wei, Lai, Vahedi, Golnaz, Kanno, Yuka, O’Shea, John J., Laurence, Arian
Publicado em 2011

A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3

Por Steward-Tharp, Scott M., Laurence, Arian, Kanno, Yuka, Kotlyar, Alex, Villarino, Alejandro V., Sciume, Giuseppe, Kuchen, Stefan, Resch, Wolfgang, Wohlfert, Elizabeth A., Jiang, Kan, Hirahara, Kiyoshi, Vahedi, Golnaz, Sun, Hong-wei, Feigenbaum, Lionel, Milner, Joshua D., Holland, Steven M., Casellas, Rafael, Powrie, Fiona, O'Shea, John J.
Publicado em 2014

Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)

Por Ghoreschi, Kamran, Jesson, Michael I., Li, Xiong, Lee, Jamie L., Ghosh, Sarbani, Alsup, Jason W., Warner, James D., Tanaka, Masao, Steward-Tharp, Scott M., Gadina, Massimo, Thomas, Craig, Minnerly, John C., Storer, Chad E., LaBranche, Timothy P., Radi, Zaher A., Dowty, Martin E., Head, Richard D., Meyer, Debra M., Kishore, Nandini, O'Shea, John J.
Publicado em 2011