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IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation
Autoimmune diseases are characterized by regulatory deficit in both the CD4+ and CD8+ T-cell compartments. We have shown that CD8+ T-cells associated with acute relapse of multiple sclerosis are significantly deficient in their immune suppressive ability. We hypothesized that distinct CD8+ cytotoxic...
में बचाया:
में प्रकाशित: | Front Immunol |
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मुख्य लेखकों: | , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Frontiers Media S.A.
2020
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7657266/ https://ncbi.nlm.nih.gov/pubmed/33193343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.568630 |
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