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IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation

Autoimmune diseases are characterized by regulatory deficit in both the CD4+ and CD8+ T-cell compartments. We have shown that CD8+ T-cells associated with acute relapse of multiple sclerosis are significantly deficient in their immune suppressive ability. We hypothesized that distinct CD8+ cytotoxic...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Immunol
मुख्य लेखकों: Renavikar, Pranav S., Sinha, Sushmita, Brate, Ashley A., Borcherding, Nicholas, Crawford, Michael P., Steward-Tharp, Scott M., Karandikar, Nitin J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657266/
https://ncbi.nlm.nih.gov/pubmed/33193343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.568630
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