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CD8(+) T-Cells as Immune Regulators of Multiple Sclerosis

The vast majority of studies regarding the immune basis of MS (and its animal model, EAE) have largely focused on CD4(+) T-cells as mediators and regulators of disease. Interestingly, CD8(+) T-cells represent the predominant T-cell population in human MS lesions and are oligoclonally expanded at the...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sinha, Sushmita, Boyden, Alexander W., Itani, Farah R., Crawford, Michael P., Karandikar, Nitin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674574/
https://ncbi.nlm.nih.gov/pubmed/26697014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00619
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