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Clonal Composition of Neuroantigen-specific CD8+ and CD4+ T-cells in Multiple Sclerosis
Patients with multiple sclerosis (MS) show a high prevalence of myelin-reactive CD8+ and CD4+ T-cell responses, which are the putative effectors/modulators of CNS neuropathology. Utilizing a novel combination of short-term culture, CFSE-based sorting and anchored PCR, we evaluated clonal composition...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092854/ https://ncbi.nlm.nih.gov/pubmed/21397340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2011.02.001 |
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