Altered expression of SIRPγ on the T-cells of relapsing remitting multiple sclerosis and type 1 diabetes patients could potentiate effector responses from T-cells

Factors regulating self-antigen directed immune-responses in autoimmunity are poorly understood. Signal regulatory protein gamma (SIRPγ) is a human T-cell specific protein with genetic variants associated with type 1 diabetes (T1D). SIRPγ’s function in the immune system remains unclear. We show that...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sinha, Sushmita, Renavikar, Pranav S., Crawford, Michael P., Steward-Tharp, Scott M., Brate, Ashley, Tsalikian, Eva, Tansey, Michael, Shivapour, Ezzatollah T., Cho, Tracey, Kamholz, John, Karandikar, Nitin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451561/
https://ncbi.nlm.nih.gov/pubmed/32853219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238070
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