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Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)
Inhibitors of the JAK family of non-receptor tyrosine kinases have demonstrated clinical efficacy in rheumatoid arthritis and other inflammatory disorders; however, the precise mechanisms by which JAK inhibition improves inflammatory immune responses remain unclear. Here we examined the mode of acti...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3108067/ https://ncbi.nlm.nih.gov/pubmed/21383241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003668 |
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