Evidence of association with type 1 diabetes in the SLC11A1 gene region

Por Yang, Jennie HM, Downes, Kate, Howson, Joanna MM, Nutland, Sarah, Stevens, Helen E, Walker, Neil M, Todd, John A
Publicado em 2011

Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes

Por Saleh, Nada M, Raj, Srilakshmi M, Smyth, Deborah J, Wallace, Chris, Howson, Joanna M M, Bell, Louise, Walker, Neil M, Stevens, Helen E, Todd, John A
Publicado em 2011

Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients

Por Downes, Kate, Marcovecchio, M. Loredana, Clarke, Pamela, Cooper, Jason D., Ferreira, Ricardo C., Howson, Joanna M. M., Jolley, Jennifer, Nutland, Sarah, Stevens, Helen E., Walker, Neil M., Wallace, Chris, Dunger, David B., Todd, John A.
Publicado em 2013

Evaluation of Single Nucleotide Polymorphism Typing with Invader on PCR Amplicons and Its Automation

Por Mein, Charles A., Barratt, Bryan J., Dunn, Michael G., Siegmund, Thorsten, Smith, Annabel N., Esposito, Laura, Nutland, Sarah, Stevens, Helen E., Wilson, Amanda J., Phillips, Michael S., Jarvis, Nancy, Law, Scott, de Arruda, Monika, Todd, John A.
Publicado em 2000

Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes s...

Por Lo Bernice, Swafford Austin DE, Shafer-Weaver Kimberly A, Jerome Lawrence F, Rakhlin Luba, Mathern Douglas R, Callahan Conor A, Jiang Ping, Davison Lucy J, Stevens Helen E, Lucas Carrie L, White Jill, von Borstel Reid, Todd John A, Lenardo Michael J
Publicado em 2011-11-01

Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes s...

Por Lo, Bernice, Swafford, Austin DE, Shafer-Weaver, Kimberly A, Jerome, Lawrence F, Rakhlin, Luba, Mathern, Douglas R, Callahan, Conor A, Jiang, Ping, Davison, Lucy J, Stevens, Helen E, Lucas, Carrie L, White, Jill, von Borstel, Reid, Todd, John A, Lenardo, Michael J
Publicado em 2011

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial

Por Cutler, Antony J., Oliveira, Joao, Ferreira, Ricardo C., Challis, Ben, Walker, Neil M., Caddy, Sarah, Lu, Jia, Stevens, Helen E., Smyth, Deborah J., Pekalski, Marcin L., Kennet, Jane, Hunter, Kara M.D., Goodfellow, Ian, Wicker, Linda S., Todd, John A., Waldron-Lynch, Frank
Publicado no Wellcome Open Res (2017)

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

Por Nejentsev, Sergey, Howson, Joanna M. M., Walker, Neil M., Szeszko, Jeffrey, Field, Sarah F., Stevens, Helen E., Reynolds, Pamela, Hardy, Matthew, King, Erna, Masters, Jennifer, Hulme, John, Maier, Lisa M., Smyth, Deborah, Bailey, Rebecca, Cooper, Jason D., Ribas, Gloria, Campbell, R. Duncan, Clayton, David G., Todd, John A.
Publicado em 2007

Postthymic Expansion in Human CD4 Naive T Cells Defined by Expression of Functional High-Affinity IL-2 Receptors

Por Pekalski, Marcin L, Ferreira, Ricardo C, Coulson, Richard M.R., Cutler, Antony J., Guo, Hui, Smyth, Deborah J., Downes, Kate, Dendrou, Calliope A., Dopico, Xaquin Castro, Esposito, Laura, Coleman, Gillian, Stevens, Helen E., Nutland, Sarah, Walker, Neil M., Guy, Catherine, Dunger, David B., Wallace, Chris, Tree, Timothy I. M., Todd, John A., Wicker, Linda S.
Publicado em 2013

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2

Por Pekalski, Marcin L., García, Arcadio Rubio, Ferreira, Ricardo C., Rainbow, Daniel B., Smyth, Deborah J., Mashar, Meghavi, Brady, Jane, Savinykh, Natalia, Dopico, Xaquin Castro, Mahmood, Sumiyya, Duley, Simon, Stevens, Helen E., Walker, Neil M., Cutler, Antony J., Waldron-Lynch, Frank, Dunger, David B., Shannon-Lowe, Claire, Coles, Alasdair J., Jones, Joanne L., Wallace, Chris, Todd, John A., Wicker, Linda S.
Publicado no JCI Insight (2017)

Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene

Por Davison, Lucy J., Wallace, Chris, Cooper, Jason D., Cope, Nathan F., Wilson, Nicola K., Smyth, Deborah J., Howson, Joanna M.M., Saleh, Nada, Al-Jeffery, Abdullah, Angus, Karen L., Stevens, Helen E., Nutland, Sarah, Duley, Simon, Coulson, Richard M.R., Walker, Neil M., Burren, Oliver S., Rice, Catherine M., Cambien, Francois, Zeller, Tanja, Munzel, Thomas, Lackner, Karl, Blankenberg, Stefan, Fraser, Peter, Gottgens, Berthold, Todd, John A.
Publicado em 2012

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial

Por Todd, John A., Evangelou, Marina, Cutler, Antony J., Pekalski, Marcin L., Walker, Neil M., Stevens, Helen E., Porter, Linsey, Smyth, Deborah J., Rainbow, Daniel B., Ferreira, Ricardo C., Esposito, Laura, Hunter, Kara M. D., Loudon, Kevin, Irons, Kathryn, Yang, Jennie H., Bell, Charles J. M., Schuilenburg, Helen, Heywood, James, Challis, Ben, Neupane, Sankalpa, Clarke, Pamela, Coleman, Gillian, Dawson, Sarah, Goymer, Donna, Anselmiova, Katerina, Kennet, Jane, Brown, Judy, Caddy, Sarah L., Lu, Jia, Greatorex, Jane, Goodfellow, Ian, Wallace, Chris, Tree, Tim I., Evans, Mark, Mander, Adrian P., Bond, Simon, Wicker, Linda S., Waldron-Lynch, Frank
Publicado no PLoS Med (2016)

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

Por Todd, John A, Walker, Neil M, Cooper, Jason D, Smyth, Deborah J, Downes, Kate, Plagnol, Vincent, Bailey, Rebecca, Nejentsev, Sergey, Field, Sarah F, Payne, Felicity, Lowe, Christopher E, Szeszko, Jeffrey S, Hafler, Jason P, Zeitels, Lauren, Yang, Jennie H M, Vella, Adrian, Nutland, Sarah, Stevens, Helen E, Schuilenburg, Helen, Coleman, Gillian, Maisuria, Meeta, Meadows, William, Smink, Luc J, Healy, Barry, Burren, Oliver S, Lam, Alex A C, Ovington, Nigel R, Allen, James, Adlem, Ellen, Leung, Hin-Tak, Wallace, Chris, Howson, Joanna M M, Guja, Cristian, Ionescu-Tirgoviste, Constantin, Simmonds, Matthew J, Heward, Joanne M, Gough, Stephen CL, Dunger, David B, Wicker, Linda S, Clayton, David G
Publicado em 2007

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

Por Wang, Thomas J., Zhang, Feng, Richards, J. Brent, Kestenbaum, Bryan, van Meurs, Joyce B., Berry, Diane, Kiel, Douglas, Streeten, Elizabeth A., Ohlsson, Claes, Koller, Daniel L., Palotie, Leena, Cooper, Jason D., O'Reilly, Paul F., Houston, Denise K., Glazer, Nicole L., Vandenput, Liesbeth, Peacock, Munro, Shi, Julia, Rivadeneira, Fernando, McCarthy, Mark I., Anneli, Pouta, de Boer, Ian H., Mangino, Massimo, Kato, Bernet, Smyth, Deborah J., Booth, Sarah L., Jacques, Paul F., Burke, Greg L., Goodarzi, Mark, Cheung, Ching-Lung, Wolf, Myles, Rice, Kenneth, Goltzman, David, Hidiroglou, Nick, Ladouceur, Martin, Hui, Siu L., Wareham, Nicholas J., Hocking, Lynne J., Hart, Deborah, Arden, Nigel K., Cooper, Cyrus, Malik, Suneil, Fraser, William D., Hartikainen, Anna-Liisa, Zhai, Guangju, Macdonald, Helen, Forouhi, Nita G., Loos, Ruth J.F., Reid, David M., Hakim, Alan, Dennison, Elaine, Liu, Yongmei, Power, Chris, Stevens, Helen E., Jaana, Laitinen, Vasan, Ramachandran S., Soranzo, Nicole, Bojunga, Jörg, Psaty, Bruce M., Lorentzon, Mattias, Foroud, Tatiana, Harris, Tamara B., Hofman, Albert, Jansson, John-Olov, Cauley, Jane A., Uitterlinden, Andre G., Gibson, Quince, Järvelin, Marjo-Riitta, Karasik, David, Siscovick, David S., Econs, Michael J., Kritchevsky, Stephen B., Florez, Jose C., Todd, John A., Dupuis, Josee, Hypponen, Elina, Spector, Timothy D.
Publicado em 2010