Common genetic determinants of vitamin D insufficiency: a genome-wide association study

BACKGROUND: Vitamin D is crucial for maintaining musculoskeletal health. Recently, vitamin D insufficiency has been linked to a number of extraskeletal disorders, including diabetes, cancer, and cardiovascular disease. Determinants of circulating 25-hydroxyvitamin D (25-OH D) include sun exposure an...

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Main Authors: Wang, Thomas J., Zhang, Feng, Richards, J. Brent, Kestenbaum, Bryan, van Meurs, Joyce B., Berry, Diane, Kiel, Douglas, Streeten, Elizabeth A., Ohlsson, Claes, Koller, Daniel L., Palotie, Leena, Cooper, Jason D., O'Reilly, Paul F., Houston, Denise K., Glazer, Nicole L., Vandenput, Liesbeth, Peacock, Munro, Shi, Julia, Rivadeneira, Fernando, McCarthy, Mark I., Anneli, Pouta, de Boer, Ian H., Mangino, Massimo, Kato, Bernet, Smyth, Deborah J., Booth, Sarah L., Jacques, Paul F., Burke, Greg L., Goodarzi, Mark, Cheung, Ching-Lung, Wolf, Myles, Rice, Kenneth, Goltzman, David, Hidiroglou, Nick, Ladouceur, Martin, Hui, Siu L., Wareham, Nicholas J., Hocking, Lynne J., Hart, Deborah, Arden, Nigel K., Cooper, Cyrus, Malik, Suneil, Fraser, William D., Hartikainen, Anna-Liisa, Zhai, Guangju, Macdonald, Helen, Forouhi, Nita G., Loos, Ruth J.F., Reid, David M., Hakim, Alan, Dennison, Elaine, Liu, Yongmei, Power, Chris, Stevens, Helen E., Jaana, Laitinen, Vasan, Ramachandran S., Soranzo, Nicole, Bojunga, Jörg, Psaty, Bruce M., Lorentzon, Mattias, Foroud, Tatiana, Harris, Tamara B., Hofman, Albert, Jansson, John-Olov, Cauley, Jane A., Uitterlinden, Andre G., Gibson, Quince, Järvelin, Marjo-Riitta, Karasik, David, Siscovick, David S., Econs, Michael J., Kritchevsky, Stephen B., Florez, Jose C., Todd, John A., Dupuis, Josee, Hypponen, Elina, Spector, Timothy D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086761/
https://ncbi.nlm.nih.gov/pubmed/20541252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(10)60588-0
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