Postthymic Expansion in Human CD4 Naive T Cells Defined by Expression of Functional High-Affinity IL-2 Receptors

As the thymus involutes with age, the maintenance of peripheral naive T cells in humans becomes strongly dependent on peripheral cell division. However, mechanisms that orchestrate homeostatic division remain unclear. In this study we present evidence that the frequency of naive CD4 T cells that exp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pekalski, Marcin L, Ferreira, Ricardo C, Coulson, Richard M.R., Cutler, Antony J., Guo, Hui, Smyth, Deborah J., Downes, Kate, Dendrou, Calliope A., Dopico, Xaquin Castro, Esposito, Laura, Coleman, Gillian, Stevens, Helen E., Nutland, Sarah, Walker, Neil M., Guy, Catherine, Dunger, David B., Wallace, Chris, Tree, Timothy I. M., Todd, John A., Wicker, Linda S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614027/
https://ncbi.nlm.nih.gov/pubmed/23418630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202914
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