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Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial

Background: The infection of a participant with norovirus during the adaptive study of interleukin-2 dose on regulatory T cells in type 1 diabetes (DILT1D) allowed a detailed insight into the cellular and cytokine immune responses to this prevalent gastrointestinal pathogen. Methods:  Serial blood,...

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Vydáno v:Wellcome Open Res
Hlavní autoři: Cutler, Antony J., Oliveira, Joao, Ferreira, Ricardo C., Challis, Ben, Walker, Neil M., Caddy, Sarah, Lu, Jia, Stevens, Helen E., Smyth, Deborah J., Pekalski, Marcin L., Kennet, Jane, Hunter, Kara M.D., Goodfellow, Ian, Wicker, Linda S., Todd, John A., Waldron-Lynch, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: F1000Research 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531165/
https://ncbi.nlm.nih.gov/pubmed/28815218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.11300.3
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