Layers of regulation in induction of mixed chimerism by anti-CD40L

Por Lucas, Carrie L., Sykes, Megan
Publicado em 2011

Identifying genetic determinants of autoimmunity and immune dysregulation

Por Lucas, Carrie L., Lenardo, Michael J.
Publicado no Curr Opin Immunol (2015)

Epstein–Barr Virus Susceptibility in Activated PI3Kδ Syndrome (APDS) Immunodeficiency

Por Carpier, Jean-Marie, Lucas, Carrie L.
Publicado no Front Immunol (2018)

Genomics of immune diseases and new therapies

Por Lenardo, Michael, Lo, Bernice, Lucas, Carrie L.
Publicado no Annu Rev Immunol (2015)

PI3Kδ and primary immunodeficiencies

Por Lucas, Carrie L., Chandra, Anita, Nejentsev, Sergey, Condliffe, Alison M., Okkenhaug, Klaus
Publicado no Nat Rev Immunol (2016)

Expression and purification of soluble murine CD40L monomers and polymers in yeast Pichia pastoris

Por Hermanrud, Christina E., Lucas, Carrie L., Sykes, Megan, Huang, Christene A., Wang, Zhirui
Publicado em 2010

Allospecific rejection of MHC class I-deficient bone marrow by CD8 T cells

Por Haspot, Fabienne, Li, Hao Wei, Lucas, Carrie L., Fehr, Thomas, Beyaz, Semir, Sykes, Megan
Publicado em 2013

Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1

Por Dornan, Gillian L., Siempelkamp, Braden D., Jenkins, Meredith L., Vadas, Oscar, Lucas, Carrie L., Burke, John E.
Publicado no Proc Natl Acad Sci U S A (2017)

A CD8 T cell–intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo

Por Fehr, Thomas, Lucas, Carrie L., Kurtz, Josef, Onoe, Takashi, Zhao, Guiling, Hogan, Timothy, Vallot, Casey, Rao, Anjana, Sykes, Megan
Publicado em 2010

LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L

Por Lucas, Carrie L., Workman, Creg J., Beyaz, Semir, LoCascio, Samuel, Zhao, Guiling, Vignali, Dario A. A., Sykes, Megan
Publicado em 2011

Novel PIK3CD mutations affecting N-terminal residues of p110δ cause APDS1 in humans

Por Takeda, Andrew J., Zhang, Yu, Dornan, Gillian L., Siempelkamp, Braden D., Jenkins, Meredith L., Matthews, Helen F., McElwee, Joshua J., Bi, Weimin, Seeborg, Filiz O., Su, Helen C., Burke, John E., Lucas, Carrie L.
Publicado no J Allergy Clin Immunol (2017)

Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K

Por Lucas, Carrie L., Zhang, Yu, Venida, Anthony, Wang, Ying, Hughes, Jason, McElwee, Joshua, Butrick, Morgan, Matthews, Helen, Price, Susan, Biancalana, Matthew, Wang, Xiaochuan, Richards, Michael, Pozos, Tamara, Barlan, Isil, Ozen, Ahmet, Rao, V. Koneti, Su, Helen C., Lenardo, Michael J.
Publicado no J Exp Med (2014)

Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes s...

Por Lo Bernice, Swafford Austin DE, Shafer-Weaver Kimberly A, Jerome Lawrence F, Rakhlin Luba, Mathern Douglas R, Callahan Conor A, Jiang Ping, Davison Lucy J, Stevens Helen E, Lucas Carrie L, White Jill, von Borstel Reid, Todd John A, Lenardo Michael J
Publicado em 2011-11-01

Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes s...

Por Lo, Bernice, Swafford, Austin DE, Shafer-Weaver, Kimberly A, Jerome, Lawrence F, Rakhlin, Luba, Mathern, Douglas R, Callahan, Conor A, Jiang, Ping, Davison, Lucy J, Stevens, Helen E, Lucas, Carrie L, White, Jill, von Borstel, Reid, Todd, John A, Lenardo, Michael J
Publicado em 2011

Mg(2+) regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D

Por Chaigne-Delalande, Benjamin, Li, Feng-Yen, O’Connor, Geraldine M., Lukacs, Marshall J., Jiang, Ping, Zheng, Lixin, Shatzer, Amber, Biancalana, Matthew, Pittaluga, Stefania, Matthews, Helen F., Jancel, Timothy J., Bleesing, Jack J., Marsh, Rebecca A., Kuijpers, Taco W., Nichols, Kim E., Lucas, Carrie L., Nagpal, Sunil, Mehmet, Huseyin, Su, Helen C., Cohen, Jeffrey I., Uzel, Gulbu, Lenardo, Michael J.
Publicado em 2013

Effective “activated PI3Kδ syndrome”–targeted therapy with the PI3Kδ inhibitor leniolisib

Por Rao, V. Koneti, Webster, Sharon, Dalm, Virgil A. S. H., Šedivá, Anna, van Hagen, P. Martin, Holland, Steven, Rosenzweig, Sergio D., Christ, Andreas D., Sloth, Birgitte, Cabanski, Maciej, Joshi, Aniket D., de Buck, Stefan, Doucet, Julie, Guerini, Danilo, Kalis, Christoph, Pylvaenaeinen, Ilona, Soldermann, Nicolas, Kashyap, Anuj, Uzel, Gulbu, Lenardo, Michael J., Patel, Dhavalkumar D., Lucas, Carrie L., Burkhart, Christoph
Publicado no Blood (2017)

Dominant-Activating, Germline Mutations in Phosphoinositide 3-Kinase p110δ Cause T Cell Senescence and Human Immunodeficiency

Por Lucas, Carrie L., Kuehn, Hye Sun, Zhao, Fang, Niemela, Julie E., Deenick, Elissa K., Palendira, Umaimainthan, Avery, Danielle T., Moens, Leen, Cannons, Jennifer L., Biancalana, Matthew, Stoddard, Jennifer, Ouyang, Weiming, Frucht, David L., Rao, V. Koneti, Atkinson, T. Prescott, Agharahimi, Anahita, Hussey, Ashleigh A., Folio, Les R., Olivier, Kenneth N., Fleisher, Thomas A., Pittaluga, Stefania, Holland, Steven M., Cohen, Jeffrey I., Oliviera, Joao B., Tangye, Stuart G., Schwartzberg, Pamela L., Lenardo, Michael J., Uzel, Gulbu
Publicado em 2013