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Layers of regulation in induction of mixed chimerism by anti-CD40L

The pathways regulating immunological tolerance are complex and overlapping. Here, we comment on our findings that the PD-1, CTLA-4, LAG-3 and TGFβ inhibitory molecules are all involved in mediating peripheral CD8 T‑cell tolerance induced by anti-CD40L and allogeneic bone marrow transplantation in m...

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Detalhes bibliográficos
Main Authors: Lucas, Carrie L., Sykes, Megan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321881/
https://ncbi.nlm.nih.gov/pubmed/22509427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chim.2.4.19053
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