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Addition of Anti-CD40 Monoclonal Antibody to Nonmyeloablative Conditioning with Belatacept Abrogated Allograft Tolerance Despite Induction of Mixed Chimerism
BACKGROUND: We recently reported anti-CD40 monoclonal antibody and rapamycin (aCD40/rapa) to be a reliable, nontoxic, immunosuppressive regimen for combined islet and kidney transplantation (CIKTx) in nonhuman primates (NHPs). In the current study, we attempted to induce allograft tolerance through...
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| Publicado no: | Transplantation |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309923/ https://ncbi.nlm.nih.gov/pubmed/30113996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000002417 |
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