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Expression and purification of soluble murine CD40L monomers and polymers in yeast Pichia pastoris

The anti-murine CD40L monoclonal antibody MR1 has been widely used in immunology research to block the CD40-CD40L interaction for induction of transplantation tolerance and to abrogate autoimmune diseases. The availability of recombinant CD40L with high binding capacity for MR1 would provide a valua...

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Detalhes bibliográficos
Main Authors: Hermanrud, Christina E., Lucas, Carrie L., Sykes, Megan, Huang, Christene A., Wang, Zhirui
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005846/
https://ncbi.nlm.nih.gov/pubmed/21074618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2010.11.006
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