A CD8 T cell–intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo

Previous studies have indicated that blockade of signaling through the T-cell receptor (TCR)/calcineurin/nuclear factor of activated T cells (NFAT) pathway impairs transplantation tolerance induced with anti-CD154 antibody. By using an allogeneic bone marrow transplantation model, we examined the ro...

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Detalhes bibliográficos
Main Authors: Fehr, Thomas, Lucas, Carrie L., Kurtz, Josef, Onoe, Takashi, Zhao, Guiling, Hogan, Timothy, Vallot, Casey, Rao, Anjana, Sykes, Megan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826238/
https://ncbi.nlm.nih.gov/pubmed/20007805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-230680
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